project-in-depth

Describing in-depth support projects

Segmenting Glomeruli and other structures from synchrotron X-ray microtomography datasets

Segmenting Glomeruli and other structures from synchrotron X-ray microtomography datasets

Diabetes is a long-lasting health condition with serious complications. We studied a new group of rats with a specific genetic mutation linked to diabetes. Regardless of their gender and blood sugar levels, these rats were overweight and had larger livers, hearts, and kidneys compared to normal rats. A study of the size of Bowmans space (difference between outer perimeter and Tuft of their glomeruli) can reveal tendencies toward having or developing cancer. In that respect advanced machine learning approaches are used to automatically segment and evaluate 3D volumetric information of many of the structures found within the tomography scans collected.

Butterflies in Virtual Reality: developing workflows for efficient morphological segmentation and analysis of X-ray microtomography Datasets

Butterflies in Virtual Reality: developing workflows for efficient morphological segmentation and analysis of X-ray microtomography Datasets

Initially an InfraVis pilot project, the VR lab at LTH has worked with Sridhar Halali, a researcher at the LU Dept. of Biology. As part of his work to understand how butterflies have evolved in response to environmental changes, Dr Halali has collected a dataset of microCT scans of butterflies. The specific trait of interest is in this case the shape of the head. It can, however, be a greatly time-consuming task to isolate body segments in a large 3-dimensional dataset using the 2D interface of the standard software (3D Slicer). This is where the VR Lab comes in, analyzing the problem, building on existing plugins for visualization and interaction in VR, and parallel processing to implement a solution to facilitate the task.

SEAD Conservation Paleobiology

SEAD Conservation Paleobiology

This project aim to demonstrate the availability of a long-term record of biodiversity data which could be used to understand the biodiversity implications of the current climate and extinction crisis. The visualisation can lead to a discussion about the regulations for sound environments, and to the initiation of new research questions about health effects.

Visualization of pedestrian noise exposure

Visualization of pedestrian noise exposure

We develop an interactive map where the impact of noise is dynamically visualised through heatmaps over the course of a day as a synthesis of pedestrian traffic and noise level at a certain place and time.​

The visualisation can lead to a discussion about the regulations for sound environments, and to the initiation of new research questions about health effects.

3D mapping of cortical changes leading to epileptic seizures

3D mapping of cortical changes leading to epileptic seizures

Epilepsies are a family of devastating disorders characterized by spontaneous, recurrent seizures. It is one of the most common brain disorders and considered the most burdensome neurologic disorder worldwide. ​Available pharmacological treatments are only symptomatic, often with side effects and fail to adequately control seizures in one third of patients.